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1.
Adjective. Used to describe blatantly overprocessed vocals on recordings, or in a more general sense, as a disparaging description of any and all aspects of overproduced records. Refers to a popular pitch-correcting plugin for Pro Tools digital recording systems.
"Someone tell Britney her voice sounds like autotune."

"Dude, could they have compressed the rhythm guitar a little more? This sounds like autotune, man!"
by Danny Delinquent December 16, 2004