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2.
1. being on drugs people are not customed to.

2. acting differently than the way people know you to. (being upset, or too hyper)
1. "she was on some other shit last night, i dont even know what that drug was called"

2. a: "why you on some other shit?"
b: "how im on other shit?"
a: "you all upset, for no reason"
by pro121c June 19, 2009
 
1.
When someone is behaving in such a way that is not normal human behavior, or typical of any known man made drug.
"She's acting crazy, that bitch is on some other shit."
by yesitsmeagain September 10, 2008