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1.
Sofo is the term for the section of the University District in Seattle, WA that lies south of 45th St.
John: Man, you live in the U-District?
James: Yeah, but its cool. I live in sofo.
by Puckey July 01, 2004
15 3
 
2.
An acronym for So Far Off. Used for people who are so far off the mark, there needs to be a new word to describe their level of sheer buffoonery and ridiculousness.
My ninety year old grandmother's sexy photos on Facebook were SOFO, I am mortified.
by Dr Neurohacker December 25, 2013
2 0
 
3.
Wise like a philosopher.
Kick ass smart.
What a sofos thing to do.
by sofos1 March 11, 2011
4 2
 
4.
The new slang word for expressing something that is fabulous and critically trendy. Its a simple acronym of "So fabulous!". The power of word spreads out entire planet.
John: Oh, check out my new glasses.
Sarah: SoFo! You shine dude!
by thefinthefword September 10, 2009
2 4
 
5.
Old San Juan, Puerto Rico is divided in half by Calle Fortaleza. The portion on the south side is called SoFo. The term was invented by Gringo transplants who can't survive without meaningless acronyms in their lives and who, after living on the island for 20 years, haven't learned to speak Spanish.
Honey, I thought we would go to the restaurant that just opened in SoFo.
by Juan787 February 15, 2008
1 4