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1. SoBo
South Bombay
SoBo is so much better than NoBo
2. sobo
short for South Boston aka southie MA, a hood in boston. No one in boston and southie calls it sobo. This is a term coined by realtors to make southie sound trendy like the back by or south end. This term is harshly rejected by long time southie residents who know its a gimmick to lure in rich yuppie bastards.
Yuppie- "I'm moving to Sobo where I will buy a condo for $500,000so I will be closer to my cube downtown"

Southie Guy- "Are ya Fackin retaded its called southie, not sobo you yuppie bastard,move back to vermont"
3. sobo
South Bound. Used in describing direction on hiking trails such as the long trail and the appalachian trail.
I'm gonna do the long trail sobo.
4. sobo
A very laidback person.
You are such a sobo.
by sobo Aug 8, 2005 add a video
5. SoBo
the state of being south of any border
She wants to go to Tijuana so I guess we'll be SoBo tonight
6. sobo
A sexual deviant, a person who sleeps with a variety of people.
That's what Sobo said.
7. sobo
slang term for the drug suboxone
Jean: "Hey Wally I'm all out of heroin, can I buy a sobo?"
Wally: "One for $10 or five for $40?"
Jean: "Can I just give you a quick Handy for one? Or I'll give you a Blumpkin for the five"
Wally: "I can't part with my sobos that easy Jean. Let me give you an angry dragon and you can have half my script"
Jean: "Ok"
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