The sharp pain that can occur when one consumes a frozen beverage (milkshake, slurpee, piña colada) too quickly. The pain is a result of the nerves sending signals to the blood vessels that supply the brain, altering the blood flow. Synonym of brainfreeze.
Chloe took a big sip of her milkshake, and immediately put her hand to her head, "Ouch! Ouch! Slurpee tumor!"