A female (human or otherwise) who is shady and not to be trusted. A woman who improves her situation through questionable means.
Ron: "I met this girl the other night. I took her home. When I woke up in the morning she was gone and so was all my money and my trees"
Markus: "Damn! what a slippery slut! If you every see her again you should take her home and donkey punch her"