Street life intelligence money is everything. Started in Harlem,NY made popular by rapper Vado.
What's poppin slime?
by J-Smooth585 June 24, 2011

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Top Definition
something used when referring to a friend
Yo what up sliiiiiime!???

Chillin, suuuup main?
by Shaaarrrp February 19, 2005

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Street Life Intelligence and Money is Everything
"Friends name" is my slime partner

-or-

What uppp sliiimme
by Lpatterson October 06, 2010

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When you are in multiple relationships or just want to cheat.

Used a lot in Toronto.
Chrissy: My boyfriend is a slime, he was talking to other girls.
via giphy
by _mitchie2323mb_ December 14, 2016

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A term used to describe cum that comes out of a persons ass after anal sex.
After Lisa and I had anal sex she had so much slime come out onto my bed.
by JesusFag October 09, 2016

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Slime is a gooey liquidy thing , it is also something Ty will not let me make for our mummification project as the guts !! It is usually green and cold.
LETS MAKE SMILE FOR THE PROJECT .... NO GABE WE ARE NOT MAKING SLIME
by Lix G Kaz Stew Meg December 14, 2016

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A mucus like substance that the Republican party is built out of.
There are many, many examples of Republican slimeballs.
by jesster79 March 13, 2005

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