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1.
Having good, rowdy sex. Refers to the sound made by bootymeat slapping on your lap.
"I had to kill dat bitch cause she was slappin' skins wit all da homies."

"Man, me and dis ho was slappin' skins all mothafuckin' night!"
by Johnny Insane July 06, 2008
 
2.
When partaking in sexual intercourse and the mans testicles slap against thee parters genitalia primarily slapping the clitoris or groin.
Last night we were slappin skin so hard i couldn't walk this morning.
by lomik November 03, 2007