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1.
A term used to describe something that is moving in a quick jumpy fashion. Often the skittish object/person is acting without purpose and lacks premeditation.
The calico cat was sleeping on the floor then became very skittish when she randomly ran around the house chasing her own tail.
by Crystal Kathrotia November 16, 2007
 
2.
close in resemblance to the word sketchy; meaning unsure , unstable or down right shady.
" Man , my dealer has been acting real skittish lately ."
by mrknowitallagain October 30, 2008
 
3.
being both scottish and british. having the same bloodlines. kinda like a mix.
that man over there is Skittish
by Wolfstock September 24, 2009