Top Definition
Injecting heroin WITHOUT DIRECT INJECTION into a vein.
I used to skin-pop, but now I mainline.
by Oldpunk September 28, 2005
throwback word of the seventies... injecting heroin into your veins with a needle.
I used to skin-pop, but then i went to mainlinin (smoking).
by marLi April 24, 2005
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