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1.
injecting once self through subcutaneous (only skin deep) methods, rather than by means of IV intravenous (into the vein) or IM intramuscular (into the muscle)
I got almost the instant rush skin poppin as i did mainlining that shit
by PHD Boystar June 08, 2007
 
2.
Skin poppin means to use intravenous drugs.
He dont sniff dope he be skin poppin.
by Ursula Rosato May 04, 2006