To have a personal stake or investment. Originally coined by Warren Buffett
Why do you care what Apple's stock is, you have no skin in the game.
by CatIsWrongAboutThis.JPG December 5, 2013
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This describes a situation in which someone is risking everything.
The bomb squad has all their skin in the game defusing the van.
by I, Wreckerrr December 2, 2016
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the act of "hooking up" with someone (making out, getting head, etc.) with somebody of the opposite sex.
Billy-Yo mayne i just got mad skin game from that dime piece girl Chelsea.

Alex- no wayy bro...you are so lucky, anybody would skin that.
by jmandy June 6, 2010
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A game played in Kik Groups used to encourage the sending of nudes should a member be caught making a spelling mistake. Usually the keyword is “skin” as it is fast and easy to type.

Different variations of the game can be found amongst different groups such as, No Corrections, False Skin Calls, Live Post Only or improper use of grammar.
Girl: I can’t belive that happened!
Boy: Skin! Post a nude!
Girl: How am I always losing the skin game?
by FlirtyMadHouse March 15, 2019
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