"Skeeze" was formed by combination of the words "skank" and "sleeze", and can be used in an adjective form, i.e. "skeezy" or "skeeze-like". Generally "skeeze" implies qualities that are lower than those of a skank, sleeze, slut, or whore.
See also: skank, sleeze/sleaze
Guy #2: "Stay away from that man.. I've heard that she has more crabs than Red Lobster, and that she let some guy piss in her mouth for $5."
Guy #1: "Holy shit.., what a skeeze..."
Yes. He said, "Do you like ponies, little girl? Cause I've got a throbbing stallion for you to ride."