To have completely lost the fucking plot for no apparent reason or for a very insignificantly miniscule excuse to express bottled up frustration and wrath.
This may be done by a sudden yell of cuss words, or by punching objects or friends nearby, or even by honking horns and driving like a wreckless maniac. Original skazzas are terrorists and typical bum speaking skips who pump drugs.
john : "bro watch out for that skazz-looking cunt"
brad : "haha piss off mate im already in a skazzing out mood anyway, fuck the worrrld nigga!!"