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1.
a nasty ass female that sleeps with anything male for drugs, money, or popularity.
ex 1. -- Kelly wanted another dime bag to snort so she blew her dealer.

ex 2. -- man that bitch sleeps with every guy at school
by Maxwell K. Davison March 25, 2003
 
2.
Fugly ass bitches who most likely have at least 4 stds and will fuck any semi living thing taht will take her/him. SHould be avoided at all cost.
Erica is an fugly skank ho, EW.
by suckassbeotch September 26, 2006
 
3.
SKANK HO
Nasty ass diseased bitches who will fuck anything with a dick or pussy to get what they want.
(Even complete strangers)
1. Missy wanted a raise at her work, so she fucked her boss in his office.

2. Missy wanted some free drinks at the local bar, so she blew and fucked a complete stranger
in the parking lot. (Only got two drinks. lol what a SKANK HO)
by the murff June 24, 2010
 
4.
common name used to describe one's ex-girl.
My skank ho ex has more aids than the entire contenent of africa
by Rammsteinick January 16, 2005
 
5.
one who "gets around", is worse than a skank, but does not meet the qualifications to be a slut.
Girl, get yo skank-ho mamma off my dog!
by tw+lb May 04, 2003
 
6.
1-A person who is neither a skank nor a ho, but who is acting in a manner that one would describe as agitating, agressive, annoying, or just downright ridiculous

2- A term of endearment for a friend whom you love very much
1-"That skank-ho just poured beer on my weave!"

2-"Hey skank-ho! What's up?"
by Lady Keats September 09, 2009
 
7.
see your mom.
"I did that skank ho indabutt last night. I mean your mom."
"Join the club."
by Nick D May 17, 2003