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1) used to express agreement or to emphasize a point stated.
2) used lieu of "duh".
3) used to refute an obviously false statement.
1) statement: "wooo, baby got back!" agreement: "sistah, puh-lease!"
2) statement: "phish sucks." response: "sistah, puh-lease!"
3) skinny girl says: "omigod, these pants make me look so fat." response: "sistah, puh-lease!"
by koscar February 10, 2005

Words related to sistah puh-lease

(4) synonymous with brutha puh-lease.
(4)see above examples for usage.
by ClamJam February 14, 2005