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1.
when an angry militant black woman goes crazy
Rufus: I tried to set LaKeisha straight but da bitch went sista souljah on my ass.
Antionio: Damn, time to put a boot in da bitchs' mouth.
by Unkkle Crakker September 29, 2006
 
2.
Sista Souljah is a rap artist and was a vocal member of Jesse Jackson's Rainbow Coalition. During the 92 riots over the Rodney King beating, Sista Souljah made several racist statements encouraging senseless black on white violence. Her sound bites not only damaged her own reputation, but ultimately damaged Jesse Jackson's credibility. Presidential candidate Bill Clinton wasted no time jumping on this, and compared Souljah (and Jesse Jackson by association) to David Duke, a former Louisiana governor who was a leader in the Ku Klux Klan.

A Sista Souljah moment is when a black person damages their reputation by making a racist statement publicly.
Kanye West had a Sista Souljah moment when he interrupted Taylor Swift's MTV Music Award acceptance speech, yanked the microphone from her hand, and declared Beyonce should have won the award instead.
by ButtSmoothie September 13, 2009