Sickle Cell trait Sickle Cell disease.
Sickle Cell trait is when you're a carrier of the gene. There aren't really any eminent medical concerns. There are limitations on what you should do that comes with the trait.
Sickle cell disease usually occurs when two people with Sickle Cell trait have a child. Sickle Cell disease can create major medical concerns such as blood sickling episodes and stroke.
Both come with the chance or higher susceptibility to Anemia.
Both are also hereditary. Most times it (in trait form) is found in African Americans. (1 in 500 African Americans have it, some don't know)