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10.
short for serial killer
after droppin those six niggas we jus started callin him serial
by S. Loc January 07, 2004
 
1.
slang for serious. Favored by Al Gore on South Park.
Al Gore: "Manbearpig is very serial."
by Forceflow15 April 27, 2006
 
2.
short for "serious"
"What? Are you serial?"
by CHOPOPJR November 03, 2003
 
3.
serial: serious. Serial is as serious as serial killers. So serious - more serious than cereal. Not as funny as cereal, but more concerned.
usu. in response: exp:

Richard, I'm pregnant!
Are you serial?
Holy rusted metal batman!
Are you serial?
by dueEast June 07, 2006
 
4.
Short for serial number. Often used for an illegal method of registering a program one does not wish to pay for.
I got a serial for photoshop last night and it worked perfectly.
by Invalid H. User April 23, 2003
 
5.
Another way to say "serious".
"Dude, I'm super serial. Why don't you believe me when I say I'm super duper serial?"
by Bryan Castillo January 09, 2008
 
6.
being very serious; dead serious.
John: "I scored with Kelly last night, it was TIGHT! man!"
Jeff: "You serial?"
John: "Hell yeah!"
Jeff: "With trix?" (aka: you're bullshitting)
John: 'No, I'm for real!"
Jeff: "Dam, mofo! Hell yeah!"
by Olgie March 30, 2010
 
7.
a gun's serial number...often scraped off to make the gun harder to trace
"serial killers tote guns without the serials"
--Streetlife in Rules (Iron Flag, Wu-Tang Clan)
by dubhex February 01, 2008