Top Definition
Nickname for TV "cook" Sandra Lee, given to her by her many detractors. Based upon the name of her show "Semi-Homemade Cooking with Sandra Lee".
Heather: I'm making chocolate truffles for dessert using canned store-bought frosting.
Taniqua: Bitch, you are such a Semi-Ho.
by Mixed Race Kid March 14, 2009

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