Top Definition
The act of taking illegal drugs or alcohol in attempt to alleviate anxiety, stress, or certain mental disorders (ie. schizophrenia & bipolar).
I'll tell you what, this job has me so stressed out that I am going home to self medicate with some hard booze.
by Almighty_AL April 19, 2005

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v. To alleviate one's self of physical or mental pain through alternative forms such as recreational drugs or alcohol
Tom: Your back is pretty bad man, go see a doctor.
Jim: Nah brah, I'll just self-medicate with a 5th of vodka
by Chris24O April 08, 2010

The Urban Dictionary Mug

Lotsa space for your liquids.

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The Urban Dictionary Mug

Lotsa space for your liquids.

Buy the mug

The Urban Dictionary Mug

Your favorite word on a white mug.

Create a mug

The Urban Dictionary Mug

One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.

Buy the mug

The Urban Dictionary T-Shirt

Soft and offensive. Just like you.

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The Urban Dictionary T-Shirt

Smooth, soft, slim fit American Apparel shirt. Custom printed. 100% fine jersey cotton, except for heather grey (90% cotton).

Buy the t-shirt