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1.
A state of being that is smaller than puny and larger than nano. If you a sick you are "puny", if you're really sick you're "scule". The short form of miniscule.
Alan started feeling scule right before he broke out in violent diarrhea, nausea, and constant sweating.
by Onassiss McCuien October 12, 2006
 
2.
Superior to the word cool
A dolphin talking is not just cool it is scule
by Stevensonston April 04, 2013
 
3.
A single cigarette of any size.
I like to smoke a scule after a big dinner
by Iam Hawk January 14, 2008