Top Definition
1. A kind of infection that one gets through having gay sex or being fondled by gay men.

2. A condition resembling herpes that can make ones face disfigured and results in red crustaceous bumps all over the skin. Bumps are usually located near penis or mouth area.

Also can be a term for someone who is a carrier of herpes simplex and other various sorted sexually transmitted diseases.
Why does he go out in public when he has Sal Disease?
by Tquat April 10, 2008

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