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3.
To leave, or prepare to leave. Popularized by an episode of Family Guy, where Peter says it.

See also, bounce, dip.
Well, I had better saddle up.
by JakeStar July 16, 2005
 
1.
1. the act of climbing into one's ride(vehicle)

2. The act of getting ready to go somewhere, especially the act of getting ready to drive somewhere

3. The act of a woman climbing on top of a man to ride him
1.Damn Jimmy, let's saddle-up, we need to get there before all the ladies are gone.

2. Aren't you ready to leave yet? Saddle-up, you slow be-yotch.

3.Ralph: Oh baby, I want you so bad!
Jenny: Sit back and relax hon, I'm about to saddle up.
by puma_blues March 29, 2004
 
2.
V. To get ready (esp. to leave).

Popularized by American "Old Western" films, where horses were the primary means of transportation. When someone saddled up their horse, it was often because they were about to leave.
"Saddle up, friend, we've got a long way to travel."
by Iskar March 29, 2004
 
4.
Get prepared to have sex
"Saddle up and prepare to ride"
by EyeA March 30, 2004
 
5.
Move into position in/on your vehicle/ride and prepare to begin moving.
Saddle up boys, these cars won't drive themselves.

I am going to saddle up the baby in the car for a trip to the store.
by DIGGERß March 28, 2004
 
6.
To engage in sexual intercourse
Right luv lets saddle up !
by bb July 18, 2003