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1. S.O.
Abbreviation for "Significant Other". The gender-neutral way to refer to someone's boy/girlfriend.
I'm having a party at my place. Bring your S.O.!
by The Grammar Nazi Nov 10, 2001 share this
2. S.O.
Means "significant other".
Hey, stop macking your S.O. and go home.
3. S.O.
Short for "Snap Off." An S.O. is a female, usually overweight and unattractive, who finds it difficult to find a male partner who will engage in sexual intercourse with her. When the S.O. finally "gets lucky", she will ride his genatalia so hard, it will snap off under the pressure.
"Oh man, you hooked up with a real ugly chick last night."

"I know had to ice my nuts because she was a real S.O."
4. S.O.
A person who alternates between Mr. Right and the Douchebag Next Door. You can recognize him by refusal to communicate while in a relationship and by a wrecked set of priorities. This guy will become a permanent asshole a month before breaking up with you.
The epitome of a S.O. would be Sean Oliver at UPenn, but S.O.s can be found throughout the country. Most abundantly at college campuses and local bars.
5. S.O.
Sexual Orifice
You know that song, Low S.O.
by slavetical Jun 2, 2003 share this
6. S.O.
Something other
I want to get a gift for her SO than the usual.
by poppi Dec 10, 2003 share this
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