Rye-a-rhea is what happens after a night of drinking large quantities of rye whiskey, when burning feces pisses out of your ass-hole. Otherwise known as the hershey-squirts.
Jay: "Wow man, you were in the bathroom for a really long time! Are you okay?"

Billy: "I went totally overboard with the rye last night, I have the worst case of rye-a-rhea ever. My cornhole is burning like wild-fire!!!"
by Jennifiend April 06, 2007

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