This is the beginning of depression. When you feel like the world is just out to get you.. nothing is going right in your life, and you're on the verge of insanity or killing yourself. Despite all that, you still go through your daily routine, holding into an ounce of hope that things will be better one day...

Then you're running on empty.
I don't know about you, but I'm running on empty.
by Nerissa September 27, 2005
A Jackson Browne song.
Running on empty, running to the sun.
by takethathill August 21, 2006
Due to chronic masturbation, this term describes the situation when a puff of air is ejaculated instead of semen.
Geez, I need to stop jerking off like it owes me money, I am running on empty.
by the quaker May 22, 2007

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