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Rule One 

The Doctor lies. (from Doctor Who)
Amy: But he (the Doctor) was dead.
River: Who told you that?
Amy: He did.
River: Rule one: the Doctor lies.

River: He said no one could save him. But he must have known I could.
The Doctor: Rule one: the Doctor lies.

River: Okay. I'm going to tell you what I probably shouldn't. The Doctor's last secret. Don't you want to know what he whispered in my ear?
Amy: He whispered his name.
River: Not his name, no.
Amy: Yeah it was. He said it was.
River: Rule one?
Amy: The Doctor lies.
Rule One by atalienay October 13, 2011
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Rule One 

The Doctor lies.

Most of River Song's "The Doctor lies" is about it being her own rule #1 for figuring out what's going on when things don't seem to make sense. If things seem incomplete or impossible, consider first if The Doctor lied about something.
Rory Williams: Why did he tell us he was dead?
River Song: Rule One: The Doctor lies. So do I.
Rule One by 10DoctorWhoFangirl10 December 8, 2011
Related Words

School Rule One 

School rule one, don't tell your teacher that you're going to cheat on your test.

Rule One 

Literal translation is 'don't be a pussy'. Most often used when berating someone with 'you forgot rule one' implying that if one has forgotten rule one then they're indeed a pussy.
Dan: I'm a little tired, my boots are chaffing and the wind is blowing in the wrong direction.
Gora: You're in violation of rule one. Get over that kicker.
Flawless usually tall and a brunette. Can makes any boys day with her beautiful smile and long legs. Boys are attracted to her appearance she is not exactly neat but does not come accros as trashy she is a boss of the school and boys dream of spending one night with her she will always have your back and loves boys with brown hair and blue eyes. She doesn't play hard to get she is. She does one or two sports is kinda fit but has a curvy appearance. Boys love talking to her because she always knows what to say. She makes jokes (all the time that make you fell uncomfortable in a good way :p). Usually popular and has a ton off friends. You would never want to lose a Rulene... Because se is a queen.
Rulene is a queen 👸
Rulene by Afrikaans ❤️ August 18, 2017

Rule One 

A rule that states anything that results in any form of labor or risk should not be taken unless the amount of money your offered is to your liking
Only fight when you have been paid to do so

Never take a Favor...you get no money out of it

Everything....and everyone has a price....

This is Rule one
Rule One by Dragyn21 April 19, 2010

Rule one 

Rule one refers to the first rule of deciding if someone is worth getting involved with: "Never put your dick in crazy". Other more gender-neutral ways of phrasing this rule such as "never invest in crazy" have been suggested, but the central meaning stays true regardless of phrasing.
A:"Oh man, do you think I should get with him?"

B:"No, chicka, he breaks rule one."

A: "Okay, not happening then."
Rule one by Owlsongbitter May 22, 2014