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1.
Despondency related to a lack of marijuana.

A play on the phrase "reefer madness," which is originally a 1936 anti-marijuana propaganda film.
Man, last week my mom smoked all my shit, and I'm broke. I had a bad case of reefer sadness.
by KoGe August 10, 2006

Words related to reefer sadness

marijuana reefer madness joint reefer week