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1.
A friendless loser, who acts queer and/or annoying. Someone who does very stupid, strange, and homosexual things.

queer + weirdo = queirdo.
John Jorge and David Thomson are such queirdos, seriously they both act like such homosexual dumbasses and are ugly, friendless, pieces of shit.
by OMG_its_amyyyy May 29, 2005
 
2.
Someone who is a complete weirdo, but is also quite queer.
God that guy is such a queirdo
by Jimmy432 November 26, 2008
 
3.
Someone who isn't exactly normal. Like, they have this weirdness about them and at the same time they're mysterious. Think of it as calling someone who's a goth this. They are very weird and vague (queer) in a way. Basically two words 'weird' or 'weirdo' and 'queer' combined.
weirdo or queer
Someone walks up to you and does this weird thing with their hands like they've just cast a spell onto you. And you say, while they're walking away, "You fucken queirdo!"
by my name is.... April 19, 2007