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An annual spring event at Radford University involving free live bands and food where students (and some faculty) begin drinking at 12pm on thursday, drink straight through the weekend, and stop drinking at 8am monday. Some years they even have to bring in the National Guard to control the drunken insanity.
"it's 10am on a friday and you're drunk already?!?"
"IT'S QUADFEST!"
quadfest by unknown April 16, 2005
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myspace quadfecta

When you get comments, messages, pic comments, and friend request when you sign in
damn yo i just got a myspace quadfecta

quagfest 

Quagfest is a celebration hosted by Glenn Quagmire in honor of his 1000th sex partner.
Appeared in the episode "Fighting Irish"
I was invited into the quagfest and the event is prefaced by a parade featuring Quagmire's sex partners from around the world.
quagfest by ProfessionalCanadian! November 11, 2015

Quadfecta 

When Mario Kart is being played, and a player gets last place all four races.
Player 1: Jim got the quadfecta!
Quadfecta by Iced_ September 1, 2017

quadfecta 

A legendary beirut/beer pong shot that lands on the tops of four cups simultaneously. Considered the rarest shot in the game, topping even the trifecta, 2-cup knockover-and-sink, and simultaneous 6-cup game-ending double bounce-in. Counts as 4 cups and has never happened in recorded history of the game, despite being theoretically possible.

So rare for the following reasons:
1) Only possible with smaller-than-average cups.
2) Only possible when cups are arranged in a perfect square formation (not possible in a standard game).
3) The physics of it happening are similar to those of the trifecta, which almost never happens in itself.
Witnessing Dan's game-ending quadfecta in the semifinals of the Theta Delt beirut tournament was a thing of beauty comparable to seeing the face of God Himself smiling down on you from the heavens.
quadfecta by Nicholas D December 24, 2007

Quadfecta 

A woman who is an impossible combination of smart, cool, funny, and beautiful.
Alicia is smart, gorgeous, funny and cool... The legendary Quadfecta.
Quadfecta by Haggernaut August 19, 2012
A cazy party at Radford. Its a magical place, where the beer flows like wine, and the women instictivly flock like the salmon of Capastrano. Im talkin of a little party known as quaddddfest
Dude, Remember that crazy ass drunkin orgy we had at quadfest with those 4 spanish chicks, or maybe they were some kind of italian?

No, i was soo hammered i couldnt even tell that i was at quadfest.
quadfest by spiderman1428 March 9, 2009