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2.
Mean the same that "man up" means to a mean. Means to dress up ect. and get all sexy and make men want to fuck them.
You got a pussy up.
by Judge dredd7 March 20, 2011
 
1.
1. Act mean towards someone.

2. Act scared/scured/cowardly towards someone.
Don't pussy up now, nigga, after talking all that shit.
by Mr. Terrence L. Trezvant September 04, 2006