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1.
to go inject heroin
lets go push off
by dopefiend November 11, 2003
 
2.
To get high, particularly by shooting up heroin.

Used frequently in the movie, "Requiem for a Dream."
"Let's get something to eat."
"We should push off first."
by Mr. Ree January 25, 2006
 
3.
an exclamation from Britain meaning, "go away or get lost!"
"What a mankey git, hey push off!" said Clara to the creepy man, attempting to make offensive smalltalk to her.
by viking_on_stilts May 01, 2007