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1.
When someone is in a state of immense frustration.
super pissed off
That makes me want to punch a baby.
What the fuck im gonna go punch some babies
by conner gfizzle May 30, 2006
 
2.
The act of being so mad you could punch a baby
I'm so mad I could punch a baby
by I Zack I June 12, 2007
 
3.
a phrase to say when your mad at something or someone regardless of the circumstances you are in.
Georgie: hey cassi! you're lookin' kinda fat today..

Cassi: Ugh gosh georgie! you make me want to punch a baby!

or

I can't believe they are making us run 5 miles today! ugh i'm so mad i could punch a baby!
by Purple Astronaut January 04, 2009