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1.
When you are getting some action and some asshat comes in and interrupts you, ruining the moment.
Used by Bubbles on Trailer Park Boys episode "Lahey's Got My Porno Tape".

"Did you see that! That's a prick job, boys."
by Rip December 12, 2005
 
2.
Someone who is struggling with their own life so badly, that you're required to yell at them from a moving car. What you yell at them, will arm them with the knowledge that they're struggling in life.
Shawn: Hey Kristian, look at this prick job on the side of the road.
Krisitain: (to the man on the side of the road) You're a fucking prick job!!
by SHenderson May 03, 2008