look up any word, like cunt:
 
1.
Football played by a bunch of drunk, hot high school girls on school nights. Being drunk their clothes get ripped off and they don't care, they just continue to play.
Man I love powderpuff. That chick got all her clothes except for her thong ripped off. What a way to spend a Tuesday night.
by the elect April 12, 2005
 
2.
flag football scrimmage between junior and senior high school girls played for fun. admission goes to "coats for kids" charity.
The seniors donminated the juniors in powder puff.
by muscles13 November 01, 2007
 
3.
A term used to describe a sissy. Someone who talks a lot of stuff but never backs it up because they can't.
"Man, I'll punch you in the face."

"Do it then."

"...."

"Man, you're a fuckin powder puff."
by Chris April 17, 2005
 
4.
Drug user, esp. cocaine
Sista Sam, my homie's "powderpuff," hoovered an entire ziploc o' coke in one slow up-the-shoot motion. . . .
by William Dean A. Garner September 11, 2003
 
5.
a person who claims to be straigh tough when on the stage or in a group but when placed on the streets is just a bitch
I hear ya spit lines like an uzi but when we put ya on the streets all the niggas call ya suzi ya powder puff
by tekblade December 18, 2006
 
6.
football with a frisby
Sarah_Ng: well im off to play powderpuff
by Netto Cash February 07, 2010
 
7.
fill your ass crack up with talcum powder and fart in your girls face, blowing powder in her face.
"I powder puffed my bitch and got a free night on the couch."
by mark 47 February 29, 2008