look up any word, like pussy:
 
2.
actually, it's a quote originally from the honeymooners, aka alice and ralph, which the show Family Guy seems to make fun of quite a bit.
One a these days Alice, one of these days... POW! Right in the Kisser!
by bandaid man December 11, 2005
 
1.
A euphamism for wifebeating from "Honeymooners".
One of these days, Alice, one of these days. Pow! Right in the kisser! Bang! Zoom! To the moon, Alice, to the moon!
by Doug March 12, 2004
 
3.
While getting a blow job right as you cum you pull out and blow your load on her face and yell "Pow right in the kisser"
Right after johnny blew his load he yelled Pow right in the kisser.
by Shaunizzle March 17, 2007
 
4.
Exclamation.

Used to describe a situation as follows.

1. After performing a handjob, and the hand is covered in jizz, the giver procedes to smush their hand in the reciever's face.

2. Nothing to do with John Wayne.
1. After Julie gave Timothy a good time, she said "Pow, right in the Kisser!" and rubbed Tim's own juices in his face.

2. Pow right in the kisser is entirely unrelated in all ways to John Wayne.
by Mmm... December 08, 2005
 
5.
Originally from Family Guy.
It means to cum in someones mouth =D
... POW! Right in the Kisser! (theres no example i can think of)
by IMbeterthanYOU! November 29, 2005