Usually used in reference to an unattainable male celebrity, this is a title given to the one person who's every word, action, or look most quickly makes the speaker's vagina wet for their cock (or fingers/tongue/whatever). It is implied that the speaker is (or would like to be) a sub with this person as their Dom in a D/s relationship; as the Pope is the leader of the Catholic church, the speaker would like for this person to be the leader of their vagina.
Michael Fassbender is the pope of my vagina
by triplenope July 22, 2014
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