Top definition
Poofyfinger is a derogatory name given to anyone who plays games too much using a mouse. It is the next generation medical term, much like how Carpal Tunnel Syndrome became known in the past fifteen years.
"Johnny, you better stop playing those games, or else you'll develop a poofyfinger"

Doctor: I'm sorry Susan, it is absolutely necessary to amputate your poofyfinger

Patient: ok
by poofyfinger November 24, 2006
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