Exceeded electrophotomicrographically as the longest recognized word in English.
You: Dude, stop smoking.
Me: I don't smoke.
You: Yes, you do.
Me: No, I have pneumonoultramicroscopicsilicovolcanoconiosis
Pneumono - Lung
Ultra Microscopic - Very small/fine
silico volcano - igneous, silica
coniosis - disease
; Black Lung
Abe: Welcome home, Son. I broke two lamps and lost all your mail. What's wrong with your wife?
Homer: Never mind, you wouldn't understand.
Abe: Protein deficiency?
Abe: Unsatisfying sex life?
Homer: N -- yes!
*NOTE* This word was actually coined in a deliberate attempt to be the longest word in the english language, although you would be hard-pressed to find it in the language dictionary as it is a medical/scientific term.
"Quiet man, I'm trying to name this condition we discovered today. Its an inflammation of the lungs caused by microscopic grains of certain types of rock."
"Hey, I smell opportunity! How long could we make this word?"
"Pretty long...I suppose we could stretch it to pneumonoultramicroscopicsilicovolcanoconiosis"