Puppy Love Syndrome: usually occurs in teenagers and it is when they think that they are in love, but in reality it is just puppy love.
Dad 1: Ya i had 2 take hi in to the doctor the other day...
Dad 2: y?
Dad 1: he has a bad case of PLS..
Dad 2: o....is that like mono?
Dad 1: nope its Puppy love syndrome....
Dad 2: o shit i hope my daughter does'nt get infected too....
by lolerskates2244454 June 07, 2009

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Parking Lot Slut. Usually a girl who fucks in school parking lots in the morning.
Hey check out that PLS. Who's she with today?
by BALLINNNNNNN January 21, 2009

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Parking lot special. When a man receives a blow job in either his or his date's car while in a public parking lot. Preferably, the PLS will occur on your first date in your date's car.
Bruce: "Hey dude how'd your date go with that whorefish you met at the car wash? Get laid?"
Eddie: "Nah but I got a PLS in the Taco Cabana parking lot"
Bruce: "Did you celebrate with a chicken quesadilla?"
by Bruce Locatelli July 26, 2011

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Pretty Little Sluts. A play off the show "Pretty Little Liars". Moslty used for making fun of it for it's slutty characters.
Dan: Yeah, my sister wouldn't give me the remote so I had to watch that stupid show pretty little liars
Tom: Oh you mean pretty little sluts, PLS?
Dan: Exactly.
by gerken flocken clocken docken March 05, 2011

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The way idiots spell "please" Plz would be correct grammar. Not pls
Kat: can i pls get $10?
Lizi: *Plz, not pls.
by Hang on November 25, 2015

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It is standing for "Please"
asl pls = Age, Sex, Location Please
Most used in AOL or other chat rooms.
by KEFE August 31, 2003

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Also know as Packanack Lake Syndrome. A disease where the afflicted has the incessant need to walk around a body of water (ie. a lake)despite the time or outside temperature. Another symptom of PLS is the habit of walking in the middle of the road surrounding the body of water, usually in groups of 2-4 people. Named after the residents of Packanack Lake, who display these characteristics most prominently.
Dude, those people had such bad PLS, I had to swerve in order not to hit them.
by RobG April 18, 2006

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