British slang for "Down Syndrome", also slang for "autism" in other areas of the UK.

This slang term was developed so that people could speak about it in public without offending those afflicted with either illness.
It is popular in the "Wales" region.
i'd hate to be afflicted with plex, that guy with plex can't even come up with anything on his own
by rus_IMN November 01, 2012

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basically a name given to a dude that loves money, bitches, sex & weed. looks good and smells great & has a great sense of humor.
I want to be like Plex when I grow up.
by Just call me Guy April 12, 2011

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To do something quickly and efficiently.
Im gonna plex through this pizza!

Lets plex and get the house cleaned so we can start drinking!
by mcb1988 March 21, 2011

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An alcoholic drink made with 3/4 a shot of vodka topped up with tobasco sauce (a celebratory drink created at UoG, South Wales.
Hey Mate, its time for your plex!
by Untitled1231 October 20, 2007

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(verb), as in "to plex"
etymology: United States 21 Century English, from the word "complex"

Shortened form of the word "complex".

1. To have or show social dysfunction in the form of emotional disturbance. (Ranting, Whining, Fighting, etc...)
2. To hold a grudge in public forum.
3. To complain.

-es; -ed; -ing

Can by used as an adjective 'plexy' to describe someone or something that has the same qualities.
1. I don't want to join that list, it's too plexy.

3. Janette is always plexing in her LiveJournal about how horrible her life is.
by chronosis September 15, 2005

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Another variation of "please" used in computer/gaming lingo. Comes from "plx" a mis-typing of "plz" which was eventually done on purpose, similar to how "own" became "pwn." Plx became plox, which later became plex.
Master Chief: "Cry moar plex!"
by trigger684654 April 10, 2008

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a grudge or problem that results in an argument or dispute short for complex
The 50 cent dis track against Shyne, Fat Joe and others
by SexyOne March 12, 2005

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