British slang for "Down Syndrome", also slang for "autism" in other areas of the UK.

This slang term was developed so that people could speak about it in public without offending those afflicted with either illness.
It is popular in the "Wales" region.
i'd hate to be afflicted with plex, that guy with plex can't even come up with anything on his own
by rus_IMN November 01, 2012
a grudge or problem that results in an argument or dispute short for complex
The 50 cent dis track against Shyne, Fat Joe and others
by SexyOne March 12, 2005
to interfear cause physical or mental duress or harm.
"He plexed him"."John is a plex robot"
by kungfublood July 18, 2003
An utterly beautiful creature that is full of perfection and sexiness. When you approach the great and powerful PLEX, you may just faint/die from his overwhelming beauty. You may also have a Morgasm because of his best friend. The Plex is very tall and fantastically handsome, he also has a spiffing body and soul-sucking eyes. Plex has a wonderful brother named THE GREAT BHUNA, he is talented on his skates. Morgasm and Plex are very good ballers.
In conclusion:

Plex is the king. My king.
Person 2: I WANT PLEX
Person 3(me): *morgasms*
by Plexfan_101 October 26, 2015

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