the inability to effectively play a multi-player video game in a position other than player one; the result of frequently playing a game yourself.
I'm not going to be able to beat him if I start every round from this position. I've been playing this game so long by myself that I'm now suffering from player one syndrome.
by eddie arias July 07, 2006
The feeling you get when you can no longer distinguish a tangible understanding of reality, you feel that you are at the centre and nothing else is real, like you are player 1 in life and that everything else only exists when you are there and that other people are only NPC's (Non-Player Characters).
I think I'm suffering from Player One Syndrome I cant tell what is real, like I'm Player 1 in my own video game.
by Keneth Palin July 09, 2014