Top Definition
extacy,oxycodone,vicodin, to many pills to name .....any kind of pain killer
yo son i got some i got some pillz, na im straight im already rollin
by Juice 55 November 10, 2007
1 more definition
An act or event that is cool, awesome, or sick.
Announcer: And Alex Ovechkin scores what could be the most amazing goal I've ever seen.
Fan 1 watching it on TV: Pillz!
Fan 2: What?
Fan 1: What do you take when you're sick?....Pills..get it?...Pillz?
Fan 2 now seeing it on replay: Oh! Dude you're right, that goal totally was pillz!
by Typical Rodzzz November 13, 2010

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