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2. pernicious
Describes something that really messes you up. Most of the time you can't tell at the beginning but before you know it, it really fucks you up.
Person 1: It ain't worth it bro, you know Prozac is pernicious. Don't take it.

Person 2: Too late, I can't get off of it now.

Person 1: Damn, I hope you don't get erectile dysfunction like that other kid.

Person 2: Too late for that too...
1. pernicious
adj. causing great harm, or death, or something else real bad.
DAMN that was a pernicious fart.
by Emetic Aug 28, 2003 add a video
3. pernicious
adj: an all purpose word for something cool, hip, or awesome; or evil, twisted, and sick. Also functions well as a nickname.
Example of cool: Dude, Lord of the Rings: ROTK was SO pernicious!

Example of evil: Our algebra homework last night was PERNICIOUS! I didn't get any sleep!
by Niph Apr 24, 2004 add a video
4. pernicious
The best type of deed!
Freyalise set up us the bomb; Yawgmoth will pay for his treachery; Freyalise performed her pernicious deed.
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