Being stoned so often that your mental state is permanently altered.
The Red Hot Chili Peppers are probably permafried by now.
Permanently-Fried. When you do so much acid you never come down completely and are never the same. Does NOT mean flash-backs, that's different.
He did way too much acid a few years ago and he's been permafried ever since.
to be permanently effected by drugs, even after not taking them for a while.
i don't think weed or acid permafry people, but cocaine will change someone for life.
v 1. to appear as if on drugs, even though one is sober.
"Wow that Mark Fry kid is perma-fried."
To have taken so many drugs your brain is irreversably fried
John Saunders went way too hard for way too long but hasnt touched drugs in 10 years. Even after such a long period of sobriety he shows signs of serious brain damage and as such is permafried
which the user of the drug (mainly LSD) feels some effects of the drug (example; sever memory loss) for a vary long time after use of the drug year possibly longer ( the conduction will get better over time but user may never feel quite the same)
Getting baked too often to where you have the effects without smoking, makes you feel stupid and lost at times
Me and my bro smoked for 10 days stright we are permafried