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1.
(1) a guy who can not lose.
(2) television show about 3 teens and their highschool
(3) The now popular tv show "scrubs" is modelled after that older show, "parker lewis cant lose"
"Not a problem"
by kegdude May 26, 2004
23 5
 
2.
To leave a location very abruptly; in a sudden hurry.

Derived from the popular 90's TV show, "Parker Lewis Can't Lose" in which the main character, Parker Lewis, and his group of close friends would sync their watches and speed off to implement one of their fool-hearted plans. The way they would speed off became synonymous to the main character's name.
Hurry and give me the keys...I've got to parker lewis before my wife comes back!
by II Shell June 13, 2007
7 0