Top Definition
A cross between a Nut case and having your panties in a bunch. If your mental, or are insane, or get worked up over something SO stupid, your a panty case.
John Howard is a panty case.
"gee mang the FDA sure is getting worked up over that new drug, they are acting like real panty cases'
by Hambo February 03, 2004
2 Words related to panty case

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