look up any word, like dirty sanchez:
 
2.
A word used by italians toward other italians meaning "Italian brother" sometimes shortened to Paisan.
"Capisci Paisano, Si o no"
"Ay paisan, how ya doin"
by tony two toes February 16, 2005
 
1.
n. means countryman or brother in Italian. The equivilent of "homie" to Italians and Italian-Americans.
Usually spelled paesano.
Sometimes shortened to paesan or paisan
Yo, howyoudoing, paisano?
by Jam Master J April 14, 2005
 
3.
Italian, usually said in reference to 'buddy, friend, mate'. Also in the diaspora used to describe Italians from same village your ancestors came from.
"You know Domenico, don't you? He's a paisano (from the same village)"

"Hey paisano"
by MatteoP November 16, 2008
 
4.
Generally describes a person from the same origin as oneself.

Paisano originates from the Italian lauguage, in which it means "Brother." It is also the equivalent to "Homie" in the U.S. and often shortened to "Paisa" in slang terms.
Cristian and Jessica are both from Panama.

Therefore Jessica can call Cristian a Paisano. (or Paisa)
by ut_baby2012 November 10, 2009
 
5.
Means "friend" in Italian.
"I think."
-me

"Hey paisano!"
-a mafian walking past a fellow mafian
by Dave June 14, 2004